Therapy For Diabetes Conclusion Or Illusion Essay

GLP-1-GASTRIN AGONIST BASED THERAPY FOR DIABETES: CONCLUSION OR ILLUSION? Keywords: diabetes mellitus, dual agonist, gastrin, GLP-1, glucose tolerance Abbreviations: ÃŽ ²-cell, pancreatic beta-cell; DDP-4, dipeptidyl peptidase-4; GLP-1, gluacgon-like-peptide-1; OGTT, oral glucose tolerance test; PPAR-ÃŽ ³, peroxisome proliferator–activated receptor-ÃŽ ³ TABLE OF CONTENTS 1. Revised Commentary 2 1.1 Main Findings 2 1.2 A Repeat of History 4 References 6 2. Feedback Received from Peers 7 2.1 First feedback form 7 2.2 Second feedback form 8 3. Response to Feedback 10 Characterised by impaired ÃŽ ²-cell and insulin function, diabetes mellitus is undoubtedly becoming a hallmark point of interest in science and pharmacology. Indeed, a wide array of antihyperglycaemic agents have been successfully developed and used for the treatment of diabetes including Type 1, Type 2, and gestational varieties. However, many of these drugs have traditionally been targeted at single molecular targets and have unknown effects on the direct turnover of ÃŽ ²-cells (Finan et al., 2015). GLP-1 agonists are one new class of drugs used to treat Type 2 diabetes and target the incretin hormone group to increase their levels in the body, thereby stimulating insulin release. GLP-1 agonists have been shown to display additional positive effects on gastric emptying and satiety following meals. Fosgerau et al., (2013) used GLP-1 agonists in conjunctionShow MoreRelatedEssay Media Madness1389 Words   |  6 Pagessocial and occupational functioning prior to the diagnosis of the i llness typically have a better prognosis than those who have a history of tense and reclusive behavior. Treatment involves a collaborative effort that includes, family therapy, cognitive-behavioral therapy, social skills training, as well as pharmacological interventions (Varcarolis 271-294). The Bad Schizophrenia is often times confused with dissociative identity disorder (split personality), although there are many manifestationsRead MoreThe Effects Of Alcoholism And Child Abuse2202 Words   |  9 Pagesways of numbing his pain through alcohol. However, to what extent did this man loose the true sight that his problem was not the molestation as a child, but his own personal needs, as an alcoholic became the real issue at hand? Never did he seek out therapy to sober up, which in return affected his family. â€Å"A couple of months after Dad lost his job, he came home with a bag of groceries† (pg. 68), through his alcoholism, he was unable to sustain a stable job which impacted his family’s life, because theyRead MoreDeveloping Management Skills404131 Words   |  1617 PagesAssessment surveys in each chapter. These diagnostic tools are designed to help you identify which specific aspects of each skill topic most warrant your personal attention. †¢ Carefully study the Behavioral Guidelines and the summary model at the conclusion of the Skill Learning section of each chapter before reading that section. These written and graphical summaries are designed to bridge the research-informed description of each topic with the skill development activities that follow. To help youRead MoreStephen P. Robbins Timothy A. Judge (2011) Organizational Behaviour 15th Edition New Jersey: Prentice Hall393164 Words   |  1573 Pagesgenerally predictable, and the systematic study of behavior is a means to making reasonably accurate predictions. When we use the term systematic study, we mean looking at relationships, attempting to attribute causes and effects, and basing our conclusions on scientific evidence—that is, on data gathered under controlled conditions and measured and interpreted in a reasonably rigorous manner. (See Appendix A for a basic review of research methods used in studies of organizational behavior.) Evidence-basedRead MoreFund amentals of Hrm263904 Words   |  1056 Pagesin such a way that you can understand it, it keeps your attention, and it provides you an opportunity for feedback. We think we’ve met each of these goals. Of course, only you can be the judge of our claim. But let’s look at how we arrived at our conclusion. To be understandable and lively means that we need to communicate with you. We make every attempt in this text to have it sound as if we were in front of your class speaking with you. Writing style is important to us. We use examples whenever possible—